After installing GX Works 2 1.501X on my Windows 8 development laptop I found out that I was not able to communicate with the PLC through the USB cable as usual. After some troubleshooting I found out that the Mitsubishi Easysocket USB drivers has not been installed properly:
This issue can easily be fixed by updating the drivers. Just follow these steps:
Device Manager should be able to find the driver and update it successfully. When the installation is done the driver should appear with the name "MITSUBISHI Easysocket Driver" like this in Device Manager: